<style>
    .sub
    {
        vertical-align: sub;
    }
    .supper
    {
        vertical-align: super;
    }
</style>
<span style="line-height: 64px; font-size: 16px; background-color: #00cc00">
    Hello <div style="display: inline-block; width: 128px; height: 90px; background-color: #2a4b8d"></div> My<br>
    Dear <div style="display: inline-block; width: 128px; height: 90px; background-color: red"></div> World
</span>
<br>
<span>
    Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet<br>
    Lorem ipsum dolor
        <span style="display: inline-block; padding: 0px; vertical-align: baseline; background-color: #9f9fff">top<br>3</span>
    sit amet<br>
    dolor<span style="vertical-align: bottom">sit der</span>
    Lorem
    <span class="sub">wer<span class="sub" style="font-size: 2em">y</span>
    </span>
        ipsud
        <span class="supper" style="font-size: 2em">
            asd
            <span class="supper" style="background-color: #00cc00">
                2lkjsd
                <span style="vertical-align: bottom; background-color: #8b3737">bottom</span>
                a
                <span style="vertical-align: top; background-color: #008800">top</span>
                kjlkds<br>
                jkkl
            </span>
        sdd
        </span>
        dolor sit amet<br>
    Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet<br>
    Lorem ipsum amet
        <span style="display: inline-block; padding: 10px; vertical-align: bottom; background-color: #2a4b8d">bottom<br>3<br>4</span>
    Lorem ipsum dolor
        <span style="display: inline-block; padding: 10px; vertical-align: top; background-color: #9f9fff">top<br>3</span>
    sit amet<br>
    Lorem ipsum amet
        <span style="display: inline-block; padding: 10px; vertical-align: top; background-color: #2a4b8d">top<br>3<br>4</span>
    Lorem ipsum dolor
        <span style="display: inline-block; padding: 10px; vertical-align: bottom; background-color: #9f9fff">bottom<br>3</span>
    sit amet<br>
    Lorem ipsum dolor
        <span style="display: inline-block; padding: 10px; vertical-align: bottom; background-color: #9f9fff">bottom<br>3</span>
    sit amet<br>
    Lorem ipsum dolor
        <span style="display: inline-block; padding: 10px; vertical-align: top; background-color: #9f9fff">top<br>3</span>
    sit amet<br>
</span>